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A new strategy for tuberculosis (TB) screening, proposed by a team of researchers led by Queen Mary University of London, provides a solution to problems with current TB screening, which does not always accurately detect disease. Simultaneously screening for both active and dormant TB infection could save lives, curtail infection rates, and rewrite the story of the continued spread of this disease.
The data from the Launch-HTN trial, announced at the 34th European Meeting on Hypertension and Cardiovascular Protection, show that lorundrostat, an aldosterone synthase inhibitor, is a safe and effective treatment for people with uncontrolled or resistant hypertension, demonstrating consistent blood pressure reductions across a large and diverse patient population. It is the largest phase three trial of an aldosterone synthase inhibitor for the treatment of hypertension.
An international team of researchers led by Professor Morris Brown FRS at Queen Mary University of London found that Baxdrostat, a drug belonging to a new class of aldosterone synthase inhibitors, led to an average fall in blood pressure of 25 mmHg. This is two to three times the reduction typically achieved by a single antihypertensive drug.
A study of almost 1,000 pregnant women in Zimbabwe found that a daily dose of a commonly used, safe and inexpensive antibiotic may have led to fewer babies being born early. Among women living with HIV, those who received the antibiotic had larger babies who were less likely to be preterm.
A major UK study has revealed that the early warning signs of multiple sclerosis (MS)—including pain, mood changes, and neurological symptoms such as numbness and tingling—may appear years before diagnosis and affect all communities in similar ways.