Biggest Brain Map Ever Shows Mouse Neurons in Stunning Detail

image via New Scientist

April 10, 2025, 3:30 PM

• •Researchers have created the largest and most detailed wiring diagram of a mammalian brain to date, by mapping cells in a cubic millimetre of a mouse’s brain tissue.
• •The high-resolution 3D map contains more than 200,000 brain cells, around 82,000 of which are neurons.
• •The work yielded insights into the basic rules that shape neural circuits in the mouse brain.

Scientists have created the largest and most detailed wiring diagram of a mammalian brain to date, by mapping cells in a cubic millimetre of a mouse’s brain tissue. The high-resolution 3D map contains more than 200,000 brain cells, around 82,000 of which are neurons. It also includes more than 500 million of the neuronal connection points called synapses and more than 4 kilometres of neuronal wiring, all found in a tiny block of tissue in a brain region involved in vision.

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