Gene therapy delivery device could allow for personalized nanomedicines on-demand

image via Phys.org - News and Articles on Science and Technology

June 26, 2025, 9:00 AM

• •A new gene therapy delivery device, NANOSPRESSO, could allow hospital pharmacies to produce personalized nanomedicines on demand.
• •This could revolutionize the treatment of rare diseases, particularly in low-resource settings, by increasing access to affordable, bespoke gene and RNA therapies.
• •The device combines nucleic acid therapeutics and lipid nanoparticles into a portable manufacturing unit.
• •It allows hospital pharmacists to create sterile, injectable nanomedicines tailored to specific genetic abnormalities, bypassing centralized drug production.
• •The system is designed to be small, self-contained, and user-friendly, and is currently in development.

A groundbreaking new device called NANOSPRESSO is set to revolutionize the treatment of rare diseases. Developed by a European research project, the device allows hospital pharmacies to create personalized nanomedicines on-site, offering a cost-effective solution to treat genetic abnormalities. This innovative approach could significantly improve access to life-changing therapies for the millions affected by rare diseases worldwide, especially in areas with limited resources. By decentralizing the production of nucleic acid nanomedicines, NANOSPRESSO aims to overcome the limitations of traditional drug development models.

Read original article