Largest genetic study to date identifies 13 new DNA regions linked to dyslexia

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September 19, 2025, 11:00 AM

• •Identified 13 new genetic loci linked to dyslexia.
• •Found genes active in early brain development.
• •Developed a polygenic index to predict reading difficulties.
• •Conducted the largest genetic analysis of dyslexia to date.

Researchers conducted the largest genome-wide association study to date on dyslexia, identifying 13 new genetic loci associated with the condition. The study involved analyzing genetic data from over 1.2 million people, revealing genes active in early brain development and supporting neuron communication. A polygenic index was created, showing potential for early identification of reading difficulties, while also finding no evidence of recent evolutionary selection for dyslexia-related genes. This research expands the understanding of dyslexia's genetic architecture and paves the way for future studies on its influences.

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