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PFAS found in most americans linked to rapid biological aging

February 26, 2026, 9:24 AM

  • PFAS chemicals, used in various products, are linked to health problems and environmental persistence.
  • The study found that PFNA and PFOSA accelerate biological aging in middle-aged men.
  • Researchers analyzed data from a US health survey and examined epigenetic markers.
  • The findings suggest the need for expanded regulations on PFAS, including newer alternatives.
  • Men may be at higher risk due to lifestyle factors, such as smoking, which can compound the damaging effects of these pollutants.
  • Individuals can limit exposure by reducing consumption of packaged foods and avoiding microwaving fast-food containers.

A recent study found that specific PFAS chemicals, known as 'forever chemicals', accelerate biological aging, particularly in middle-aged men. Researchers analyzed data from a US health survey, measuring PFAS levels and epigenetic markers in blood samples. They discovered a strong link between higher levels of PFNA and PFOSA and faster epigenetic aging in men aged 50-64. The study suggests that newer PFAS alternatives may not be low-risk replacements and calls for expanded regulations to include them.

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Dr. Xiangwei LiDr. Ya-Qian Xu

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